Intended use of the test kit
This One-Step Test is intended to use as practical/routine screening test that can be done in a few minutes. This test kit is designed to detect Rabies antigen by use of a Rapid Immunochromatic Assay (RM).
Principle of the test kit
The Rabies antigen One-Step is based on a chromatographic principle in which two monoclonal antibodies react with two different, well conserved, epitopes of Rabies Virus. One monoclonal antibody is conjugated to colloidal gold particles and the other monoclonal antibody is immobilized on the test strip in the test zone “T”. Rabies Virus antigen, in the sample that is applied to the test strip at the sample zone “S”, will bind to the colloidal gold particles which then migrate to zone ”T”. A colour change in zone “T” indicates a positive test. Rabies Virus antigen is also immobilized on the test strip in the control zone “C”, which binds the colloidal gold particles to indicate that the test is working properly.
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